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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPR2
All Species:
26.06
Human Site:
S667
Identified Species:
52.12
UniProt:
P20594
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20594
NP_003986.2
1047
117022
S667
I
T
D
Y
G
L
A
S
F
R
S
T
A
E
P
Chimpanzee
Pan troglodytes
XP_001168194
1047
116964
S667
I
T
D
Y
G
L
A
S
F
R
S
T
A
E
P
Rhesus Macaque
Macaca mulatta
XP_001085221
1047
116990
S667
I
T
D
Y
G
L
A
S
F
R
S
T
A
E
P
Dog
Lupus familis
XP_531993
999
112273
E642
K
K
L
W
T
A
P
E
L
L
S
G
N
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6VVW5
1047
117039
S667
I
T
D
Y
G
L
A
S
F
R
S
T
A
E
P
Rat
Rattus norvegicus
P16067
1047
117109
S667
I
T
D
Y
G
L
A
S
F
R
S
T
A
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517544
743
84256
Y421
A
L
R
N
G
P
F
Y
V
E
G
M
D
L
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001084176
1082
122776
S703
I
T
D
Y
G
L
G
S
F
Q
S
S
C
E
T
Zebra Danio
Brachydanio rerio
XP_689479
1088
124806
S709
I
T
D
Y
G
L
A
S
F
R
S
S
C
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07553
1163
130896
E675
I
S
D
F
G
L
H
E
L
K
A
G
Q
E
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09435
1137
128085
N707
L
A
E
Y
G
M
D
N
L
V
E
E
Q
T
P
Sea Urchin
Strong. purpuratus
P16065
1125
126238
E716
I
T
D
Y
G
L
N
E
F
K
K
G
Q
K
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.8
89.1
N.A.
98.5
98.5
N.A.
64.5
N.A.
72.2
58.1
N.A.
32.5
N.A.
28.7
36.2
Protein Similarity:
100
99.9
100
90
N.A.
99.4
99.3
N.A.
67
N.A.
82.9
69.7
N.A.
49
N.A.
46.7
52.2
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
6.6
N.A.
66.6
80
N.A.
33.3
N.A.
20
46.6
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
6.6
N.A.
80
86.6
N.A.
60
N.A.
46.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
0
9
50
0
0
0
9
0
42
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% C
% Asp:
0
0
75
0
0
0
9
0
0
0
0
0
9
0
0
% D
% Glu:
0
0
9
0
0
0
0
25
0
9
9
9
0
67
9
% E
% Phe:
0
0
0
9
0
0
9
0
67
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
92
0
9
0
0
0
9
25
0
0
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
75
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
9
0
0
0
0
0
0
0
17
9
0
0
9
0
% K
% Leu:
9
9
9
0
0
75
0
0
25
9
0
0
0
9
9
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
9
0
0
9
9
0
0
0
0
9
0
9
% N
% Pro:
0
0
0
0
0
9
9
0
0
0
0
0
0
9
50
% P
% Gln:
0
0
0
0
0
0
0
0
0
9
0
0
25
0
9
% Q
% Arg:
0
0
9
0
0
0
0
0
0
50
0
0
0
0
0
% R
% Ser:
0
9
0
0
0
0
0
59
0
0
67
17
0
0
9
% S
% Thr:
0
67
0
0
9
0
0
0
0
0
0
42
0
9
9
% T
% Val:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% V
% Trp:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
75
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _